Package: GrowthCurveME Title: Mixed-Effects Modeling for Growth Data Version: 0.1.11.9000 Authors@R: c( person(given = "Anand", family = "Panigrahy", email = "anand_panigrahy@dfci.harvard.edu", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-2130-2089")), person(given = "Sonam", family = "Bhatia", email = "sonam_bhatia@dfci.harvard.edu", role = "ctb", comment = c(ORCID = "0000-0002-0124-2621")), person(given = "Thomas", family = "Quinn", email = "thomasw_quinn@dfci.harvard.edu", role = "dtc"), person(given = "Aniket", family = "Shetty", email = "aniket_shetty@dfci.harvard.edu", role = "rev"), person(given = "Keith", family = "Ligon", email = "keith_ligon@dfci.harvard.edu", role = "fnd", comment = c(ORCID = "0000-0002-7733-600X")), person(given = "Center for Patient-Derived Models", family = "Dana-Farber Cancer Institute", email = "models@dfci.harvard.edu", role = "cph")) Description: Simple and user-friendly wrappers to the 'saemix' package for performing linear and non-linear mixed-effects regression modeling for growth data to account for clustering or longitudinal analysis via repeated measurements. The package allows users to fit a variety of growth models, including linear, exponential, logistic, and 'Gompertz' functions. For non-linear models, starting values are automatically calculated using initial least-squares estimates. The package includes functions for summarizing models, visualizing data and results, calculating doubling time and other key statistics, and generating model diagnostic plots and residual summary statistics. It also provides functions for generating publication-ready summary tables for reports. Additionally, users can fit linear and non-linear least-squares regression models if clustering is not applicable. The mixed-effects modeling methods in this package are based on Comets, Lavenu, and Lavielle (2017) as implemented in the 'saemix' package. Please contact us at models@dfci.harvard.edu with any questions. License: GPL (>= 3) Depends: R (>= 4.0.0) Imports: dplyr (>= 1.1.4), flextable (>= 0.9.6), ggplot2 (>= 3.5.1), investr (>= 1.4.2), knitr (>= 1.46), magrittr (>= 2.0.3), minpack.lm (>= 1.2-4), moments (>= 0.14.1), patchwork (>= 1.2.0), rlang (>= 1.1.3), saemix (>= 3.3), stringr (>= 1.5.1), tibble (>= 3.2.1), tidyr (>= 1.3.1), viridis (>= 0.6.5) Suggests: rmarkdown (>= 2.27), testthat (>= 3.2.1.1) Encoding: UTF-8 LazyData: true Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Config/testthat/edition: 3 URL: https://github.com/cancermodels-org/GrowthCurveME BugReports: https://github.com/cancermodels-org/GrowthCurveME/issues Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libfribidi-dev make libharfbuzz-dev libicu-dev libjpeg-dev libpng-dev libtiff-dev libuv1-dev libwebp-dev libxml2-dev libssl-dev Repository: https://cancermodels-org.r-universe.dev Date/Publication: 2025-04-11 13:01:55 UTC RemoteUrl: https://github.com/cancermodels-org/growthcurveme RemoteRef: HEAD RemoteSha: fca97387512939ad8c28f1097bd6ae2a1ecf8040 NeedsCompilation: no Packaged: 2026-07-15 06:15:24 UTC; root Author: Anand Panigrahy [aut, cre] (ORCID: ), Sonam Bhatia [ctb] (ORCID: ), Thomas Quinn [dtc], Aniket Shetty [rev], Keith Ligon [fnd] (ORCID: ), Center for Patient-Derived Models Dana-Farber Cancer Institute [cph] Maintainer: Anand Panigrahy